Search results for "Lyme arthritis"

showing 3 items of 3 documents

Lyme arthritis in Southern Norway - an endemic area for Lyme Borreliosis

2014

Published version of an article in the journal: BMC Infectious Diseases. Also available from the publisher at: http://dx.doi.org/10.1186/1471-2334-14-185 Open Access Background: Despite Southern Norway is an endemic area for Lyme borreliosis there is a lack of data on Lyme arthritis (LA). In the literature controversies exist if acute LA can develop into chronic arthritis. Our objective was to identify and characterize patients with LA in Southern Norway and explore disease course after antibiotic treatment.Methods: Patients aged 20 years or older with arthritis and a positive serology for Borrelia burgdorferi infection (IgG and/or IgM) suspected of having LA were consecutively recruited ei…

AdultMalemedicine.medical_specialtyPathologyEndemic DiseasesLyme ArthritisDisease courseLyme diseaseMedical microbiologymedicineHumansBorrelia burgdorferiAgedAged 80 and overLyme DiseasebiologyNorwayLyme borreliosisbusiness.industryEndemic areaChronic arthritisMiddle Agedbiology.organism_classificationmedicine.diseaseDermatologyInfectious DiseasesVDP::Medisinske Fag: 700::Helsefag: 800FemalebusinessResearch Article
researchProduct

Invariant natural killer T cells act as an extravascular cytotoxic barrier for joint-invading Lyme Borrelia

2014

CXCR6-GFP(+) cells, which encompass 70% invariant natural killer T cells (iNKT cells), have been found primarily patrolling inside blood vessels in the liver. Although the iNKT cells fail to interact with live pathogens, they do respond to bacterial glycolipids presented by CD1d on liver macrophage that have caught the microbe. In contrast, in this study using dual laser multichannel spinning-disk intravital microscopy of joints, the CXCR6-GFP, which also made up 60-70% iNKT cells, were not found in the vasculature but rather closely apposed to and surrounding the outside of blood vessels, and to a lesser extent throughout the extravascular space. These iNKT cells also differed in behavior,…

CellMice TransgenicSpleenjoint iNKT cellsGranzymesMicegranzyme BmedicineAnimalsHumansCytotoxic T cellBorrelia burgdorferiImmunity CellularLyme DiseaseMice Inbred BALB CMultidisciplinarybiologyLyme arthritisNatural killer T cellbiology.organism_classificationGranzyme Bmedicine.anatomical_structureLiverGranzymeOrgan SpecificityBorrelia burgdorferiCD1DImmunologybiology.proteinNatural Killer T-CellsJointsJoint DiseasesSpleen
researchProduct

OP0113 Lyme arthritis in southern norway - an endemic area for lyme borreliosis

2013

Background Southern Norway is an endemic area for Lyme borreliosis. IgG antibodies against Borrelia burgdorferi sensu lato ( Bb ) has been found in approx. 20% of the population (1). The main attention in Norway has been on neuroborreliosis (2). Despite the fact that arthritis is a well-known manifestation of Bb infection there is a lack of data on Lyme arthritis (LA). Objectives To characterize patients suggestive of having LA in southern Norway. Methods According to protocol patients aged 18 years or older with arthritis with a positive serology for Bb infection (IgG and/or IgM) suspicious of having LA were consecutively recruited either from general practitioners or from our own departme…

education.field_of_studymedicine.medical_specialtybusiness.industryImmunologyPopulationArthritisJoint effusionmedicine.diseaseLyme ArthritisGeneral Biochemistry Genetics and Molecular BiologySurgerySerologyLyme diseaseRheumatologyInternal medicineRheumatoid arthritismedicineImmunology and AllergyPolyarthritismedicine.symptomeducationbusinessAnnals of the Rheumatic Diseases
researchProduct